Role played by interleukin-1 (IL-1) in the regulation of nerve growth factor (NGF) synthesis under physiological and pathophysiological conditions

Mechanisms of nerve growth factor mRNA r

Mechanisms of nerve growth factor mRNA regulation by interleukin-1β in hippocampal cultures: Role of second messengers

✍ W. J. Friedman; N. Altiok; B. B. Fredholm; H. Persson 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 912 KB

Cytokines such as interleukin-1, which are found in the brain after trauma, regulate expression of nerve growth factor (NGF) mRNA and protein in hippocampal cultures. We have investigated possible mechanisms by which 11-1p regulates NGF in hippocampal cells. The induction of NGF mRNA by 11-1p was bl