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Role ofAPCand DNA mismatch repair genes in the development of colorectal cancers

✍ Scribed by Satya Narayan; Deodutta Roy

Book ID
119901892
Publisher
BioMed Central
Year
2003
Tongue
English
Weight
781 KB
Volume
2
Category
Article
ISSN
1476-4598

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## Abstract Lynch syndrome is defined by the presence of germline mutations in mismatch repair (MMR) genes. Several models have been recently devised that predict mutation carrier status (Myriad Genetics, Wijnen, Barnetson, PREMM and MMRpro models). Families at moderate‐high risk for harboring a Ly