Role of weak interactions in thermal stability of proteins
β Scribed by B. Syed Ibrahim; Vasantha Pattabhi
- Book ID
- 116289472
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 465 KB
- Volume
- 325
- Category
- Article
- ISSN
- 0006-291X
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## Abstract Nonbonding interactions are essential for protein stability and maintenance of secondary structure. Their strength, however, is not always experimentally accessible. One example is the stability of collagen, which is in part due to BuergiβDuntiz or __n__ β Ο\* interactions between the p
## Abstract Thermal stability shift analysis is a powerful method for examining binding interactions in proteins. We demonstrate that under certain circumstances, proteinβprotein interactions can be quantitated by monitoring shifts in thermal stability using thermodynamic models and data analysis m