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Role of TRAF2/GCK in melanoma sensitivity to UV-induced apoptosis

โœ Scribed by Ivanov, Vladimir N; Kehrl, John H; Ronai, Ze'ev


Book ID
110062761
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
651 KB
Volume
19
Category
Article
ISSN
0950-9232

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## Abstract Tumor necrosis factorโ€related apoptosisโ€inducing ligand (TRAIL) has been shown to induce apoptosis in numerous transformed cell lines but not in most normal cells. Although this selectivity offers a potential therapeutic application in cancer, not all cancers are sensitive to TRAILโ€medi