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Role of Topology in the Cooperative Collapse of the Protein Core in the Sequential Collapse Model. Folding Pathway of α-Lactalbumin and Hen Lysozyme

✍ Scribed by Bergasa-Caceres, Fernando; Rabitz, Herschel A.


Book ID
126954854
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
64 KB
Volume
105
Category
Article
ISSN
0022-3654

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Relating contact order to the rate of co
✍ Fernando Bergasa-Caceres; Herschel A. Rabitz 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 168 KB

In this Letter the kinetics of the cooperative collapse phase of the protein folding pathway within the sequential collapse model (SCM) is studied. The SCM predicts an approximate linear dependence between the logarithm of the rate of collapse and the contact order of the native topology of the coll