SWI/SNF chromatin remodeling enzyme ATPa
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Nathalie Cohet; Kathleen M. Stewart; Rajini Mudhasani; Ananthi J. Asirvatham; Ch
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Article
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2010
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John Wiley and Sons
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English
β 596 KB
## Abstract The ATPase subunits of the SWI/SNF chromatin remodeling enzymes, Brahma (BRM) and Brahmaβrelated gene 1 (BRG1), can induce cell cycle arrest in BRM and BRG1 deficient tumor cell lines, and mice heterozygous for Brg1 are preβdisposed to breast tumors, implicating loss of BRG1 as a mechan