ROLE OF THYMIDINE PHOSPHORYLASE IN AN IN VITRO MODEL OF HUMAN BLADDER CANCER INVASION
β Scribed by JONES, ADAM; FUJIYAMA, CHISATO; TURNER, KEVIN; CRANSTON, DAVID; WILLIAMS, KAYE; STRATFORD, IAN; BICKNELL, ROY; HARRIS, ADRIAN L.
- Book ID
- 122028891
- Publisher
- Lippincott Williams and Wilkins
- Year
- 2002
- Tongue
- English
- Weight
- 412 KB
- Volume
- 167
- Category
- Article
- ISSN
- 0022-5347
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Thymidine phosphorylase (TP) is expressed at higher levels in a variety of human cancers than in adjacent normal tissue. It is reported that the higher expression is associated with an increase of intratumoral microvessel density and a poor prognosis. We investigated the role of TP in human non smal
## Background: Thymidine phosphorylase (tp) has angiogenic activity in various cancer tissues. gastric carcinomas are classified into two histologic groups: differentiated and undifferentiated adenocarcinomas. there are differences in the modes of development and the extent of infiltration between
## Abstract Thymidine phosphorylase (TP), also known as βplateletβderived endothelial cell growth factorβ (PDβECGF), is an enzyme, which is upregulated in a wide variety of solid tumors including breast and colorectal cancers. TP promotes tumor growth and metastasis by preventing apoptosis and indu