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Role of Three-Dimensional Matrix Stiffness in Regulating the Response of Human Neural Cells to Toxins

โœ Scribed by Ramamoorthi, Kalpith; Hara, Jared; Ito, CadeEllis; Asuri, Prashanth


Book ID
125379142
Publisher
Springer
Year
2014
Tongue
English
Weight
552 KB
Volume
7
Category
Article
ISSN
1865-5025

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The role of matrix stiffness in regulati
โœ Rebecca G. Wells ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 625 KB

Matrix stiffness (resistance to deformation), one of the many mechanical forces acting on cells, is increasingly appreciated as an important mediator of cell behavior. It regulates cell signaling broadly, with effects on growth, survival, and motility. Although the stiffness optima for different kin