Dihydrofolate reductase activity is required for many biosynthetic pathways including nucleotide synthesis. Its expression is therefore central to cellular growth, and it has become a key target for cancer chemotherapy. Transcription of the dihydrofolate reductase gene is regulated with growth, bein
Role of the Rb/E2F pathway in cell growth control
β Scribed by Joseph R. Nevins; Gustavo Leone; James DeGregori; Laszlo Jakoi
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 98 KB
- Volume
- 173
- Category
- Article
- ISSN
- 0021-9541
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