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Role of the proteasome in protein oxidation and neural viability following low-level oxidative stress

✍ Scribed by Qunxing Ding; Kristi Reinacker; Edgardo Dimayuga; Vidya Nukala; Jennifer Drake; D.Allan Butterfield; Jay C. Dunn; Sarah Martin; Annadora J. Bruce-Keller; Jeffrey N. Keller

Book ID
117105513
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
217 KB
Volume
546
Category
Article
ISSN
0014-5793

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The proteasome and its role in the degra
The proteasome and its role in the degradation of oxidized proteins
✍ Tobias Jung; Tilman Grune πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 277 KB

## Abstract The generation of free radicals and the resulting oxidative modification of cell structures are omnipresent in mammalian cells. This includes the permanent oxidation of proteins leading to the disruption of the protein structure and an impaired functionality. In consequence, these oxidi