Role of the PD-1 Pathway in the Immune R
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L. V. Riella; A. M. Paterson; A. H. Sharpe; A. Chandraker
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Article
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2012
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John Wiley and Sons
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English
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Understanding immunoregulatory mechanisms is essential for the development of novel interventions to improve long-term allograft survival. Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, have emerged as critical inhibitory signaling pathways that regulate T cell response and maintain per