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Role of the PD-1 Pathway in the Immune Response

โœ Scribed by L. V. Riella; A. M. Paterson; A. H. Sharpe; A. Chandraker


Book ID
117963593
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
735 KB
Volume
12
Category
Article
ISSN
1600-6135

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Role of the PD-1 Pathway in the Immune R
โœ L. V. Riella; A. M. Paterson; A. H. Sharpe; A. Chandraker ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 735 KB

Understanding immunoregulatory mechanisms is essential for the development of novel interventions to improve long-term allograft survival. Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, have emerged as critical inhibitory signaling pathways that regulate T cell response and maintain per