Role of the P2X7 receptor in the osteogenic differentiation of mesenchymal cells and in osteoclast fusion
β Scribed by Wang, Ning; Gartland, Alison
- Book ID
- 121626671
- Publisher
- Springer Netherlands
- Year
- 2013
- Tongue
- English
- Weight
- 110 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1573-9538
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This study addresses the role of bone morphogenetic protein-7 (BMP-7) in chondrogenic and osteogenic differentiation of human bone marrow multipotent mesenchymal stromal cells (BM MSCs) in vitro. BM MSCs were expanded and differentiated in the presence or absence of BMP-7 in monolayer and three-dime
## Abstract There is a need to develop improved methods for directing and maintaining the differentiation of human mesenchymal stem cells (hMSC) for regenerative medicine. Here, we present a method for embedding cells in defined protein microenvironments for the directed osteogenic differentiation