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Role of the Na+ /K+ /Cl− transporter in the positive inotropic effect of ouabain in cardiac myocytes

✍ Scribed by Rivka Panet; Ruhama Fixler; David Snyder; Shmuel Raz; Henri Atlan; Yael Eilam; Yonathan Hasin


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
686 KB
Volume
145
Category
Article
ISSN
0021-9541

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✦ Synopsis


In this study we have characterized the bumetanide-sensitive K+/Na+/CIcotransport in cultured rat cardiac myocytes. 1) It carries about 10% of the total K + influx. 2) It is sensitive to furosemide (Ki ,,,= 10P'M) and bumetanide


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