Role of the medial prefrontal cortex in 5-HT1A receptor-induced inhibition of 5-HT neuronal activity in the rat
✍ Scribed by Mihály Hajós; Éva Hajós-Korcsok; Trevor Sharp
- Book ID
- 110004260
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 223 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0007-1188
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## Abstract In this study, we examined the interaction of 5‐HT~1A~ and 5‐HT~2A~ receptors in the rat medial prefrontal cortex (mPFc) using the techniques of extracellular single unit recording and microiontophoresis. The iontophoresis of the selective 5‐HT~1A~ receptor agonist (±)‐8‐hydroxy‐2‐(di‐n
Serotonin, (5-HT3) receptors are found in high density in the mesocorticolimbic dopamine (DA) system (Kilpatrick et al., 1987). It has been suggested that 5-HT3 antagonists inhibit mesolimbic portions of this DA system involved in brain-stimulation reward and drug-induced reward, and that this inhib