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Role of the maternal acute phase response and tumor necrosis factor alpha in the developmental toxicity of lipopolysaccharide in the CD-1 mouse

✍ Scribed by Tyra M. Leazer; Brenda Barbee; Marian Ebron-McCoy; Gerelyn A. Henry-Sam; John M. Rogers


Book ID
114273817
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
158 KB
Volume
16
Category
Article
ISSN
0890-6238

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Exposure of pregnant CD-1 mice to methanol (MeOH) by inhalation on gestation days (gd) 6-15 results in dose-related increases in fetal cleft palate, exencephaly, and skeletal defects. Here, critical periods for the developmental toxicity of MeOH were assessed in pregnant CD-1 mice exposed to 10,000