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Role of the interferon-inducible IFI16 gene in the induction of ICAM-1 by TNF-α

✍ Scribed by Simone Sponza; Marco De Andrea; Michele Mondini; Francesca Gugliesi; Marisa Gariglio; Santo Landolfo


Book ID
113527173
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
499 KB
Volume
257
Category
Article
ISSN
0008-8749

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## Abstract IFI 16 is a member of the HIN‐200 family of transcriptional regulators that suppress cell growth, modulate the cell cycle and have been linked to cellular differentiation. We hypothesized that the activity of IFI 16 depends on its level of expression and therefore studied the transcript