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Role of the ecto-nucleotidases in the cooperative effect of adenosine and neuropeptide-S on locomotor activity in mice

✍ Scribed by Robson Pacheco; Bruna Bardini Pescador; Bruna Pescador Mendonça; Saulo Fábio Ramos; Remo Guerrini; Girolamo Calo’; Vanessa Moraes de Andrade; Elaine Cristina Gavioli; Carina Rodrigues Boeck

Book ID
113842257
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
329 KB
Volume
99
Category
Article
ISSN
0091-3057

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## Abstract ## Objective Evidence from in vitro, in vivo, and clinical studies indicates that adenosine mediates, at least in part, the antiinflammatory effects of methotrexate (MTX), although the biochemical events involved have not been fully elucidated. This study was undertaken to investigate