Role of the cytokine environment and cytokine receptor expression on the generation of functionally distinct dendritic cells from human monocytes

Molecular and genomic characterization o

Molecular and genomic characterization of human DLEC, a novel member of the C-type lectin receptor gene family preferentially expressed on monocyte-derived dendritic cells

✍ Ignacio Arce; Pedro Roda-Navarro; María C. Montoya; Patricia Hernanz-Falcón; Ama 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 204 KB 👁 3 views

We have identified a novel gene encoding a protein designated DLEC (dendritic cell lectin), which is a type II membrane glycoprotein of 213 amino acids and belongs to the human calcium-dependent (C-type) lectin family. The cytoplasmic tail of DLEC lacks consensus signaling motifs and its extracellul