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Role of the CYP2D6, EPHX1, MPO, and NQO1 genes in the susceptibility to acute lymphoblastic leukemia in Brazilian children

โœ Scribed by Vanessa da Silva Silveira; Renata Canalle; Carlos Alberto Scrideli; Rosane Gomes de Paula Queiroz; Luiz Gonzaga Tone

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
118 KB
Volume
51
Category
Article
ISSN
0893-6692

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โœ Maja Krajinovic; Hugues Sinnett; Chantal Richer; Damian Labuda; Daniel Sinnett ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 124 KB

## Abstract Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. The genetic factors underlying the susceptibility to this disease remain elusive. The enzymes CYP2E1, MPO and NQO1 are involved in the biotransformation of a variety of xenobiotics present in organic solvents, tobac