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Role of the cyclic AMP-dependent pathway in free radical-induced cholesterol accumulation in vascular smooth muscle cells

✍ Scribed by Gesquère, L.; Loreau, N.; Blache, D.


Book ID
122943254
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
141 KB
Volume
151
Category
Article
ISSN
0021-9150

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Cyclic AMP induces morphological changes
✍ Stéphane Pelletier; Catherine Julien; Michel R. Popoff; Nathalie Lamarche-Vane; 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 724 KB

## Abstract Cyclic AMP (cAMP) is a pleiotropic second messenger that regulates numerous cellular processes. In vascular smooth muscle cells (VSMCs), these include cell proliferation, migration, and contractility. Here we show that cAMP‐elevating agents induce dramatic morphological changes in VSMCs