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Role of the Conformational Versatility of the Neurotrophin N-Terminal Regions in Their Recognition by Trk Receptors

✍ Scribed by Stanzione, Francesca; Esposito, Luciana; Paladino, Antonella; Pedone, Carlo; Morelli, Giancarlo; Vitagliano, Luigi


Book ID
119207479
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
610 KB
Volume
99
Category
Article
ISSN
0006-3495

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## Abstract Orexins‐A and B, also called hypocretins‐1 and 2, respectively, are neuropeptides that regulate feeding and sleep‐wakefulness by binding to two orphan G protein‐coupled receptors named orexin‐1 (OX~1~R) and orexin‐2 (OX~2~R). The sequences and functions of orexins‐A and B are similar to