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Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection

✍ Scribed by Anna Schurich; Pooja Khanna; A. Ross Lopes; Ki Jun Han; Dimitra Peppa; Lorenzo Micco; Gaia Nebbia; Patrick T.F. Kennedy; Anna-Maria Geretti; Geoffrey Dusheiko; Mala K. Maini


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
1007 KB
Volume
53
Category
Article
ISSN
0270-9139

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Human leukocyte antigen B27 (HLA-B27) is associated with protection in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. This protective role is linked to single immunodominant HLA-B27-restricted CD8+ T-cell epitopes in both infections. In order to define the relative contrib