Role of the cardiolipin-adriamycin complex in mitochondrial toxicity
β Scribed by E. Goormaghtigh; J.-M. Ruysschaert
- Publisher
- Elsevier Science
- Year
- 1984
- Weight
- 599 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0166-6622
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Quantitative determination of cardiolipin from two mitochondrial electron-transferring complexes was achieved using a rapid and sensitive silicic acid HPLC method combined with digital analysis of the elution profile. Phospholipid samples containing as little as 0. 01 nmol of cardiolipin were accura
## Abstract The role of maternal toxicity in lovastatinβinduced developmental toxicity in rats was examined in a series of studies. The first study administered lovastatin at 100, 200, 400, or 800βmg/kg/day (mkd) orally to mated rats from Gestation Day (GD) 6 through 20. Maternal toxicity was obser