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Role of the Buffer Cation in Determining DNA Binding Constants for Metal Complexes

✍ Scribed by Kalsbeck, William A.; Thorp, H. Holden

Book ID
127238841
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
345 KB
Volume
33
Category
Article
ISSN
0020-1669

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✍ Laura Itzhaki; Sarah Weinberger; Nurit Livnah; Elisha Berman πŸ“‚ Article πŸ“… 1990 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 641 KB

## Abstract Binding of chromomycin A~3~ (CRA) to calf thymas DNA was investigated in the presence of divalent cations using visible absorption and ^1^H‐nmr spectroscopies. An apparent equilibrium binding constant (∼ 10^11^__M__^βˆ’1^) was obtained from metal competition experiments using EDTA to remo