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Role of the adenyl cyclase system in stimulation of immunogenesis by bacterial lipopolysaccharide and by endogenous serum pyrogen

✍ Scribed by O. Sh. Dzheksenbaev; V. P. Selezneva; V. T. Loginova

Publisher
Springer US
Year
1976
Tongue
English
Weight
149 KB
Volume
81
Category
Article
ISSN
0007-4888

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2-ketobutyrate and its analogues were found to inhibit strongly and transiently the rate of beta-galactosidase synthesis in Escherichia coli K12. This effect was ascribed to a strong and transient inhibition of the adenylate cyclase activity. By using pts mutants, we showed, in agreement with our pr