## Role of TGF- in Oncogenesis Transforming growth factor- (TGF-) is the founding member of a large and growing family of growth factors with regulatory properties of a multitude of cellular processes including cell proliferation, differentiation, motility, adhesion, and death. Given this multi
Role of TGF-β in immune-evasion of cancer
✍ Scribed by Christian Beck; Hans Schreiber; Donald A. Rowley
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 147 KB
- Volume
- 52
- Category
- Article
- ISSN
- 1059-910X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Transforming growth factor-beta (TGF-beta) signaling is initiated following heterodimerization of the type II TGF-beta receptor (TbetaRII) with the type I TGF-beta receptor (TbetaRI). Both receptors are required for TGF-beta responsiveness. In the present study, we characterized the actions of TGF-b
The mouse skin model of chemical carcinogenesis has been very well characterized with respect to epigenetic changes, which occur during tumour cell initiation, promotion and progression. The use of transgenic and gene knock-out mice has contributed greatly to knowledge in this area. The H-ras geneti
Retinoic acid (RA) plays an important role in embryogenesis, by regulating morphogenesis, cell proliferation, differentiation, and extracellular matrix production. RA exposure on gestational day (GD) 12 in CD-1 mice results in delayed palatal shelf elevation and subsequent clefts in the secondary pa