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Role of T cell-replacing factor (TRF) produced by monoclonal T-cell hybridoma in B-cell differentiation

✍ Scribed by K. Takatsu; S. Tomita; Y. Sano; T. Hamaoka


Book ID
113132359
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
95 KB
Volume
70
Category
Article
ISSN
0008-8749

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## Abstract The effect of T cell‐replacing factor (TRF) on B cells was studied in spleen cell cultures from athymic nu/nu mice with particular emphasis on its possible role in proliferation and/or differentiation of precursor cells. In contrast to B cell mitogens, such as lipopolysaccharide, TRF d