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Role of stereotactic biopsy in the diagnosis and management of brain tumors

โœ Scribed by Mark D. Krieger; Parakrama T. Chandrasoma; Chi-Shing Zee; Michael L. J. Apuzzo


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
702 KB
Volume
14
Category
Article
ISSN
8756-0437

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โœฆ Synopsis


Stereotactic biopsy has evolved as a powerful and safe tool to provide tissue diagnoses with minimal disruption of normal functioning brain. It plays a significant role in the management of malignant brain tumors, where the benefit of open surgery might not justify the concomitant risks. Stereotactic procedures are closed procedures, and thus direct feedback is not provided to the surgeon during manipulation of brain tissue. This difference from most other neurosurgical procedures necessitates rigor in the preoperative workup, the planning of the procedure, and the conduct of the procedure. The success of the procedure is measured by the ability of the team to make an accurate histopathological diagnosis of the lesion; in experienced hands, the rate of success should exceed 95%. Complications and mortality can be minimized with appropriate attention to detail.


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## Abstract ## Background The United Kingdom Children's Cancer Study Group (UKCCSG) Wilms Tumor Study 3 has adopted preoperative chemotherapy for Wilms tumors (WT), but required prechemotherapy biopsy for histologic diagnosis. The aims of this review were to assess the usefulness and safety of pre