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Role of STAT3/5 and Bcl-2/xL in 2-methoxyestradiol-induced endoreduplication of nasopharyngeal carcinoma cells

✍ Scribed by C.M. Ting; Chris K.C. Wong; R.N.S. Wong; K.W. Lo; Anne W.M. Lee; George S.W. Tsao; Maria L. Lung; N.K. Mak

Book ID
112142336
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
751 KB
Volume
51
Category
Article
ISSN
0899-1987

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## Background: Inhibition of apoptosis, or programmed cell death, may be critical both in the development of cancer and in determining response to therapy. the authors examined the expression of two related apoptotic inhibitors, bcl-2 and bcl-xl, in pretreatment biopsies from a series of 42 patient