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Role of retinoic acid receptor in steatohepatitis-related tumor formation

โœ Scribed by Goshi Shiota

Book ID
108951129
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
888 KB
Volume
22
Category
Article
ISSN
0815-9319

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Retinoic acid receptor ฮฑ dominant negati
Retinoic acid receptor ฮฑ dominant negative form causes steatohepatitis and liver tumors in transgenic mice
โœ Atsushi Yanagitani; Sadako Yamada; Sakiko Yasui; Takashi Shimomura; Rie Murai; Y ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 529 KB

Although attention has focused on the chemopreventive action of retinoic acid (RA) in hepatocarcinogenesis, the functional role of RA in the liver has yet to be clarified. To explore the role of RA in the liver, we developed transgenic mice expressing RA receptor (RAR) alpha- dominant negative form