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Role of Receptor Tyrosine Kinase Transmembrane Domains in Cell Signaling and Human Pathologies †

✍ Scribed by Li, Edwin; Hristova, Kalina


Book ID
120403109
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
166 KB
Volume
45
Category
Article
ISSN
0006-2960

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Many extracellular signals elicit Ca2 + mobilization and diacylglycerol formation in their target cells. Diacylglycerol is derived from the receptor-linked phosphoinositide turnover and serves as a second messenger for the activation of protein kinase C in the presence of Ca2+ and phosphatidylserine