## Abstract In the present study, we investigated the neurotoxicity of bisphenol A [BPA; 2,2‐bis‐(4 hydroxyphenyl) propane] and the underlying mechanisms of action in mouse hippocampal HT‐22 cells. BPA, known to be a xenoestrogen, is used in the production of water bottles, cans, and teeth suture m
✦ LIBER ✦
Role of reactive oxygen species in brucein D-mediated p38-mitogen-activated protein kinase and nuclear factor-κB signalling pathways in human pancreatic adenocarcinoma cells
✍ Scribed by Lau, S T; Lin, Z X; Leung, P S
- Book ID
- 110000292
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 827 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0007-0920
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## Abstract Blood vessel injury results in limited oxygen tension and diffusion leading to hypoxia, increased anaerobic metabolism, and elevated production of acidic metabolites that cannot be easily removed due to the reduced blood flow. Therefore, an acidic extracellular pH occurs in the local mi