The formation of bone occurs normally by one of two developmental processes: intramembranous or endochondral ossification. Endochondral ossification occurs in the morphogenesis of the limb buds and growth plates, and in the regeneration of bone following injury (fracture callus). Two classes of diff
Role of proteoglycans in endochondral ossification: Inhibition of calcification
β Scribed by Dominic D. Dziewiatkowski; Larry L. Majznerski
- Book ID
- 110555410
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 510 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1432-0827
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Endochondral ossification involves an ordered progression from cell division through hypertrophic differentiation to cell death. The apoptotic nature of chondrocyte death was first suggested by characteristic changes in morphology; and more recently by the pattern of DNA fragmentation and other char
## Abstract Using a rat fracture model, we investigated the effects of a decrease in serum levels of thyroid hormone on the fractureβrepair process. Rats were divided into the following groups: (a) controls, (b) those treated with methimazole for the duration of the experiment, and (c) those treate