## Abstract The ability of enterocytes to secrete electrolytes and water into the intestinal lumen represents a critical feature of mucosal defense. During disease, this function may be altered and may initiate or exacerbate pathological conditions. Although many of the intracellular mechanisms lin
Role of proteinase-activated receptors in cutaneous biology and disease
β Scribed by Anke Rattenholl; Martin Steinhoff
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 225 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0272-4391
No coin nor oath required. For personal study only.
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## Abstract ## Objective To investigate the role of proteinaseβactivated receptor 4 (PARβ4) in mediating joint inflammation and pain in mice. ## Methods Knee joint blood flow, edema, and pain sensitivity (as induced by thermal and mechanical stimuli) were assessed in C57BL/6 mice following intra