Role of protein kinases in antitumor drug resistance
✍ Scribed by H. Grunicke; J. Hofmann; I. Utz; F. überall
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 677 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0939-5555
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Many extracellular signals elicit Ca2 + mobilization and diacylglycerol formation in their target cells. Diacylglycerol is derived from the receptor-linked phosphoinositide turnover and serves as a second messenger for the activation of protein kinase C in the presence of Ca2+ and phosphatidylserine