Role of polyproline II conformation in human tropoelastin structure
โ Scribed by Brigida Bochicchio; Antonietta Pepe
- Book ID
- 102796917
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 1008 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0899-0042
No coin nor oath required. For personal study only.
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## Abstract Elastin, the protein responsible for tissue elasticity, is contained in arterial walls, lungs, and skin. Given the cassettelike organization of the human tropoelastin gene, giving rise to alternating exons encoding for crosslink domains and elastomeric domains, it is tempting to suggest
## Abstract Polyproline II (PPII) helix is an extended secondary structure present in a number of proteins. PPIIโcontaining sequences mediate specific proteinโprotein interactions with partners containing appropriate cognate domains called PPIIโrecognizing domains (PRDs) and are involved in the act