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Role of plasma lipoproteins in modifying the biological activity of hydrophobic drugs

โœ Scribed by Kishor M. Wasan; Shawn M. Cassidy

Book ID
109388976
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
167 KB
Volume
87
Category
Article
ISSN
0022-3549

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A measurement of the hydrophobic character of the drug substrate, henceforward termed as the hydrophobic effect (HE), to complex stability is established through the observed linear correlation of the free energy of 1:1 complex formation (ฮ”G K 11 = -RTlnK 11 x ) with the free energy of inherent dru