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Role of PKC and TGF-β Receptor in Glucose-Induced Proliferation of Smooth Muscle Cells

✍ Scribed by Yutaka Yasuda; Jiro Nakamura; Yoji Hamada; Mikihiro Nakayama; Sadao Chaya; Keiko Naruse; Eitaro Nakashima; Koichi Kato; Hideki Kamiya; Nigishi Hotta

Book ID
115587398
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
128 KB
Volume
281
Category
Article
ISSN
0006-291X

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TGF-β-induced protein βig-h3 is upregulated by high glucose in vascular smooth muscle cells
✍ Sung-Woo Ha; Jong-Sup Bae; Hye-Jin Yeo; Suk-Hee Lee; Je-Yong Choi; Yoon-Kyung So 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 329 KB

## Abstract TGF‐β‐induced gene‐h3 (βig‐h3) is an adhesive molecule that interacts with integrins. Because TGF‐β plays an important role in diabetic complications and βig‐h3 serves as a cell substrate, we hypothesized that diabetic conditions might increase βig‐h3 synthesis in vascular smooth muscle