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Role of peroxynitrite in methamphetamine-induced dopaminergic neurotoxicity and sensitization in mice

✍ Scribed by Syed F. Ali; Paul Haung; Yossef Itzhak

Book ID: 110881014
Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 273 KB
Volume: 5
Category: Article
ISSN: 1355-6215
DOI: 10.1111/j.1369-1600.2000.tb00200.x

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Previous studies have suggested a role for the retrograde messenger, nitric oxide (NO), in methamphetamine (METH)-and 1-methyl-4-phenyl-1,2,3,6tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Since evidence supported the involvement of the neuronal nitric oxide synthase (nNOS) isoform i