Role of Peptide Hydrophobicity in the Mechanism of Action of -Helical Antimicrobial Peptides
β Scribed by Chen, Y.; Guarnieri, M. T.; Vasil, A. I.; Vasil, M. L.; Mant, C. T.; Hodges, R. S.
- Book ID
- 125846595
- Publisher
- American Society for Microbiology
- Year
- 2006
- Tongue
- English
- Weight
- 930 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0066-4804
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Antimicrobial peptides have been isolated and characterized from tissues and organisms representing virtually every kingdom and phylum, ranging from prokaryotes to humans. Yet, recurrent structural and functional themes in mechanisms of action and resistance are observed among peptides of widely div
The increasing resistance of bacteria to conventional antibiotics resulted in a strong effort to develop antimicrobial compounds with new mechanisms of action. Antimicrobial peptides seem to be a promising solution to this problem. Many studies aimed at understanding their mode of action were descri