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Role of p27 in tamoxifen response in breast cancer cell lines

โœ Scribed by S Nilsson, C Holm, G Landberg


Book ID
120699502
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
461 KB
Volume
11
Category
Article
ISSN
1465-5411

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## Abstract Mutations in the tumor suppressor gene __TP53__ are associated with poor prognosis in breast cancer. This prognostic value may rely in part on the fact that p53 plays a role in the antiproliferative and apoptotic activities of chemotherapy regimens used to treat breast tumors. However,