Experimental cholestasis induced by ligation of the common bile duct results in morphological and functional changes in the rat hepatocyte. The aim of this study was to evaluate the adaptive response of the transport process involved in the enterohepatic circulation of bile salts to obstructive chol
β¦ LIBER β¦
Role of Nuclear Receptors in the Adaptive Response to Bile Acids and Cholestasis: Pathogenetic and Therapeutic Considerations
β Scribed by Zollner, Gernot; Marschall, Hanns-Ulrich; Wagner, Martin; Trauner, Michael
- Book ID
- 120380368
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 407 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1543-8384
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BACKGROUND: Derivatives of retinol (vitamin A), commonly referred to as retinoids, signal through retinoic acid and retinoid X receptors (RARs/RXRs) and are essential for normal limb formation. Retinoid imbalances or perturbations in receptor function result in aberrant limb development. To examine