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Role of nonsteroidal anti-inflammatory drug-activated gene-1 in docetaxel-induced cell death of human colorectal cancer cells with different p53 status

✍ Scribed by Il-Yeob Kim; Su-Young Park; Youra Kang; Dinesh Thapa; Han Gon Choi; Jung-Ae Kim

Book ID
107642431
Publisher
Springer
Year
2011
Tongue
English
Weight
860 KB
Volume
34
Category
Article
ISSN
0253-6269

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## Abstract Genistein is an isoflavenoid found in soy that has anti‐tumorigenic activities. Treatment of colorectal carcinoma HCT‐116 cells with 50 μM genistein results in a 50% reduction in cell proliferation and a 6‐fold increase in apoptosis. Genistein induces nonsteroidal anti‐inflammatory drug