Role of nitric oxide in the contraction of circular muscle in the rat portal vein
โ Scribed by Keiichi Shimamura; Li-Bo Zou; Kyoko Matsuda; Fumiko Sekiguchi; Kazuo Yamamoto; Satoru Sunano
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 52 KB
- Volume
- 440
- Category
- Article
- ISSN
- 0031-6768
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Systemic and especially splanchnic arterial vasodilation accompany chronic portal hypertension. Different soluble mediators causing this vasodilation have been proposed, the strongest evidence being for nitric oxide (NO). No data exist if structural vascular changes may partly account for this vasod
This study examined whether an increased activity of the endothelium-derived relaxing factor, nitric oxide, may account for the hyporesponsiveness to vasoconstrictors in portal hypertension. W e performed dose-response curves to methoxamine, an eadrenoceptor agonist, with and without N"dtr0-Larginin
receptors to adenylyl cyclase and K / channel opening. 24 The ton, DC. activation of inhibitory guanine nucleotide regulatory pro-
This study investigated the effect of vasopressin on portal-systemic collaterals in portal hypertensive rats and the influence of nitric oxide (NO) and prostaglandin on the responsiveness of collateral vessels to vasopressin. The vascular responsiveness to graded concentrations of vasopressin was te