𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Role of nitric oxide in the activation of NF-κB, AP-1 and NOS II expression in articular chondrocytes

✍ Scribed by A. F. Mendes; A. P. Carvalho; M. M. Caramona; M. C. Lopes

Publisher
SP Birkhäuser Verlag Basel
Year
2002
Tongue
English
Weight
134 KB
Volume
51
Category
Article
ISSN
1420-908X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Differential roles of hydrogen peroxide
Differential roles of hydrogen peroxide and superoxide in mediating IL-1-induced NF-κB activation and iNOS expression in bovine articular chondrocytes
✍ Alexandrina Ferreira Mendes; M. Margarida Caramona; A. Pato Carvalho; M. Celeste 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 259 KB

## Abstract Our previous studies showed that reactive oxygen species (ROS) are required for the pro‐inflammatory cytokine interleukin‐1β (IL‐1) to induce the activity of the Nuclear transcription Factor‐kappaB (NF‐κB) and the expression of the inducible isoform of the nitric oxide synthase (iNOS) i

Cytokine-stimulated inducible nitric oxi
Cytokine-stimulated inducible nitric oxide synthase expression in astroglia: Role of Erk mitogen-activated protein kinase and NF-κB
✍ Joshua S. Marcus; Sharon L. Karackattu; Melissa A. Fleegal; Colin Sumners 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 308 KB 👁 1 views

## Abstract Expression of inducible nitric oxide synthase (iNOS), which leads to the production of nitric oxide (NO), is stimulated by proinflammatory cytokines such as interleukin‐1β (IL‐1β) and tumor necrosis factor‐α (TNF‐α). Here we report on the roles of nuclear factor‐κB (NF‐κB) and mitogen‐a

TNFα suppresses link protein and type II
TNFα suppresses link protein and type II collagen expression in chondrocytes: Role of MEK1/2 and NF-κB signaling pathways
✍ Cheryle A. Séguin; Suzanne M. Bernier 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 413 KB

## Abstract Tumor necrosis factor α (TNFα) inhibits matrix synthesis by chondrocytes in rheumatoid arthritis and osteoarthritis; however, the underlying signaling pathways are poorly characterized. This study investigated the TNFα‐activated pathways regulating expression of two key components of th