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Role of nitric oxide and septide-insensitive NK1 receptors in bronchoconstriction induced by aerosolised neurokinin A in guinea-pigs

✍ Scribed by Fabio L M Ricciardolo; Marcello Trevisani; Pierangelo Geppetti; Jay A Nadel; Silvia Amadesi; Claude Bertrand


Book ID
110004838
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
159 KB
Volume
129
Category
Article
ISSN
0007-1188

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The K+ salt of Tbi-Hyp-Trp -OTfb (S19572, Tbi = 1-[4-(2H-tetrazol-5-yl)butyl]-lH-indole-3-carbonyl; Tfb = 3,5-di-trifluoromethyl-benzyl) is a chemically modified, water-soluble derivative designed from prolyl-tryptophan using N-and Cterminal substitutions to confer on the analogs receptor selectivit