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Role of NGF on the promotion of cell survival in basal forebrain cholinergic neurons

✍ Scribed by Hatanaka, Hiroshi


Book ID
123215578
Publisher
Elsevier Science
Year
1990
Weight
57 KB
Volume
11
Category
Article
ISSN
0921-8696

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Mouse 3T3 fibroblasts were genetically modified by transfection with a mammalian expression vector containing the rat p-nerve growth factor (NGF) gene. The transfected cell line, designated 3E, contains several hundred copies of the rat NGF gene and secretes high levels of biologically active NGF. P