Role of natural killer cells in hormone-independent rapid tumor formation and spontaneous metastasis of breast cancer cells in vivo
✍ Scribed by Md. Zahidunnabi Dewan; Hiroshi Terunuma; Masahiro Takada; Yuetsu Tanaka; Hiroyuki Abe; Tetsutaro Sata; Masakazu Toi; Naoki Yamamoto
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Weight
- 284 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0167-6806
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## Background: The mechanisms by which surgical injury fosters tumor growth are examined. ## Methods: Ta3ha mouse breast tumor line and its subline (ta3ad) differing in their metastatic abilities as tested by two models were used. in model a, ta3ha/ta3ad tumors were grown in the mammary fat pads
## Abstract We previously established an osteolytic bone metastasis model with multiorgan dissemination in natural killer (NK) cell‐depleted severe combined immunodeficient (SCID) mice using human small cell lung cancer cells (SBC‐5), which highly express the parathyroid hormone‐related protein (PT