Role of MRI in osteosarcoma for evaluation and prediction of chemotherapy response: correlation with histological necrosis
β Scribed by Jyoti Bajpai; Shivanand Gamnagatti; Rakesh Kumar; Vishnubhatla Sreenivas; Mehar Chand Sharma; Shah Alam Khan; Shishir Rastogi; Arun Malhotra; Rajni Safaya; Sameer Bakhshi
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 495 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0301-0449
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## Abstract ## BACKGROUND In primary central highβgrade osteosarcoma, a number of distinct subtypes have been identified, but little is known about the response to chemotherapy. ## METHODS The authors investigated whether the subtypes correlated with histologic response to chemotherapy in 1058 p
The maximum pixel counts taken over the tumor divided by those taken of a background region yielded a tumor-to-background ratio. The percentage of change 1 Nuclear Medicine Service, Memorial Sloanin the tumor-to-background ratio before and after chemotherapy, defined as the Kettering Cancer Center,