Immediate hypersensitivity to indoor or outdoor allergens is strongly associated with asthma or hay fever, respectively. Recent progress has defined the sequences, tertiary structures and enzymatic functions of many of the proteins involved; furthermore, the immune responses to these proteins have b
Role of mouse allergens in allergic disease
β Scribed by Elizabeth C. Matsui
- Book ID
- 107533267
- Publisher
- Current Science Inc.
- Year
- 2009
- Tongue
- English
- Weight
- 276 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1529-7322
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A considerable number of cDNAs coding for allergens have been isolated and expressed. Structural and immunological similarities between recombinant allergens and natural allergens indicate that a sufficient panel of recombinant allergens can be produced for diagnosis and therapy of allergic diseases
## Abstract Allergy is a Th2βmediated disease that involves the formation of specific IgE antibodies against innocuous environmental substances. The prevalence of allergic diseases has dramatically increased over the past decades, affecting up to 30% of the population in industrialized countries. T